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C3FIT and Beyond: Pioneering Extended Stroke Transition Care Models

C3FIT, a 23-hospital post-discharge trial studying a 12-month intervention after a stroke, was a PCORI-funded pragmatic, comparative effectiveness trial designed to compare an “integrated stroke practice unit” (ISPU) model of care to usual stroke care over 12-months post-discharge. C3FIT primary and secondary outcomes were presented at the 2025 ISC Conference in a Late Breaking Science Main Session.
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Key Takeaways from ISC 2025: How Negative Trials Still Shape Stroke Care

The 2025 International Stroke Conference (ISC) showcased new science and global best practices in stroke care. While several late-breaking trials showed no benefit, such findings still advance science and may already influence patient outcomes and practice. Here, we summarize key trials to help you review published data or track upcoming publications.
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New Year Program Guideline Check In

We are well into 2025 and deep into winter in the Northern Hemisphere.  In the spirit of a year in review, we thought it might be helpful to overview the key Clinical Practice Guidelines and Scientific Statements from 2024.  Did you miss any of these publications?  
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Re-engaging Nursing Staff in Your Stroke Program

We explore the national statistics around the nursing shortage and talk about ideas to engage new nursing staff in stroke program initiatives.
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Increasing Stroke Program Focus on Social Drivers of Health (SDoH)

Understanding the social drivers of health (SDoH) and health-related social needs (HRSN) is critical to creating equitable care for patients.
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Stroke Program Research in the Non-Academic Setting

It might seem like a huge leap for programs operating in non-academic environments to meet the requirement for patient-centered research when seeking a Comprehensive Stroke Center designation. But we’ve seen many programs successfully navigate this challenge.
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